This page uses Javascript. Your browser either doesn't support Javascript or you have it turned off. To see this page as it is meant to appear please use a Javascript enabled browser.
Print Document
View Excel Document
Cover
Document and Entity Information
Financial Statements
CONSOLIDATED BALANCE SHEETS
CONSOLIDATED BALANCE SHEETS (Parenthetical)
CONSOLIDATED STATEMENTS OF OPERATIONS AND COMPREHENSIVE LOSS
CONSOLIDATED STATEMENTS OF OPERATIONS AND COMPREHENSIVE LOSS (Parenthetical)
CONSOLIDATED STATEMENTS OF SHAREHOLDERS' EQUITY
CONSOLIDATED STATEMENTS OF CASH FLOWS
Notes to Financial Statements
General business information
Summary of significant accounting policies
Collaboration arrangements and concentration of credit risk
Fair value measurement
Property, plant and equipment, net
Right-of-use asset and lease liabilities
Intangible assets
Accrued expenses and other current liabilities
Long-term debt
Shareholders' equity
Share-based compensation
Expenses by nature
Other non-operating income / (expense)
Income taxes
Basic and diluted earnings per share
Commitments and contingencies
Related party transaction
Subsequent events
Accounting Policies
Summary of significant accounting policies (Policies)
Notes Tables
Summary of significant accounting policies (Tables)
Collaboration arrangements and concentration of credit risk (Tables)
Fair value measurement (Tables)
Property, plant and equipment, net (Tables)
Right-of-use asset and lease liabilities (Tables)
Intangible assets (Tables)
Accrued expenses and other current liabilities (Tables)
Long-term debt (Tables)
Share-based compensation (Tables)
Expenses by nature (Tables)
Other non-operating income / (expense) (Tables)
Income taxes (Tables)
Basic and diluted earnings per share (Tables)
Notes Details
Summary of significant accounting policies (Details)
Summary of significant accounting policies - Recently adopted Accounting Pronouncements (Details)
Collaboration arrangements and concentration of credit risk - BMS collaboration - Narrative (Details)
Collaboration arrangements and concentration of credit risk - Amounts owed by BMS (Details)
Collaboration arrangements and concentration of credit risk - Chiesi collaboration (Details)
Fair value measurement - Changes in Level 3 items (Details)
Fair value measurement - BMS warrants - Narrative (Details)
Fair value measurement - Sensitivity analysis on warrants (Details)
Fair value measurement - Hercules loan facility and Contingent consideration (Details)
Property, plant and equipment, net - Summary of PP&E (Details)
Property, plant and equipment, net - PP&E by geographic region (Details)
Right-of-use asset and lease liabilities - Narrative (Details)
Right-of-use asset and lease liabilities - Operating lease liabilities (Details)
Intangible assets - Summary of acquired licenses (Details)
Intangible assets - Future amortization expense (Details)
Intangible assets - Carrying amount of Licenses (Details)
Accrued expenses and other current liabilities (Details)
Long-term debt (Details)
Shareholders' equity (Details)
Share-based compensation - Summary of share-based compensation expense and unrecognized costs (Details)
Share-based compensation - Option activity and weighted-average assumptions (Details)
Share-based compensation - RSU activity (Details)
Share-based compensation - PSU activity (Details)
Share-based compensation - Employee Share Purchase Plan - Narrative (Details)
Share-based compensation - 2012 Plan option activity (Details)
Expenses by nature - Operating expenses excluding expenses presented in other expenses (Details)
Expenses by nature - Employee-related expenses (Details)
Other non-operating income / (expense) (Details)
Income taxes - Loss before income taxes and income tax benefit / (expense) (Details)
Income taxes - Tax rate reconciliation (Details)
Income taxes - Significant components of deferred taxes (Details)
Income taxes - Changes in valuation allowance (Details)
Income taxes - Effective Tax Rate (Details)
Income taxes - Tax losses expiring (Details)
Basic and diluted earnings per share (Details)
Related party transaction (Details)
All Reports
Rendering Log